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目的探讨长期服用蚓激酶或小剂量阿司匹林对脑梗死复发的预防作用。方法对127例脑梗死患者进行回顾性调查,分别统计分析42例(观察组)长期服用蚓激酶(22例,一日120~180U,服药时间>150 d)或小剂量肠溶阿司匹林(20例,一日50~70 mg,服药时间>150 d)的患者及85例(对照组)未正规服用抗凝药物患者的脑梗死复发率。结果脑梗死复发率观察组为9.52%,对照组为30.58%,前者明显低于后者(P<0.05)。结论长期服用蚓激酶或小剂量肠溶阿司匹林对脑梗死复发有一定的预防作用。
Abstract：AIM To explore the effect of lumbrukinase(Lum) or small dose of aspirin(Asp) on prevention of ischemic stroke recurrence.METHODS The 127 ischemic stroke patients were retrospectively investigated.Forty-two patients administered with Lum or small dose of Asp and 85 patients without regular use of anticoagulant drugs were compared for observing the recurrence of ischemic stroke.RESULTS The recurrence rate with prevention group was less than that of without preventive drugs(9.52% vs 30.58%).CONCLUSION Lum or small dose of Asp is effective in prevention of ischemic stroke and no ADR are found.
[1]李忠.缺血性脑血管病[M].北京:科学技术出版社,2003:2-3.
[2]邵承斌.蚯蚓纤溶酶研究与应用进展[J].渝州大学学报,1999,16(3):47.
[3]David SG.Richard AP,Thomas C,et al.Intravenous ancrod for treatmentof acute ischemic stroke:The STAT study:a randomized controlled trial[J].JAMA,2002,283(18):2395.
[4]刘红君,高凤琴.百奥蚓激酶与常规药物临床脑梗塞治疗疗效观察[J].齐齐哈尔医学院学报,2002,23(2):3.
基本信息:
DOI：10.19577/j.cnki.issn10074406.2006.02.014
中图分类号:R743.33
引用信息:
[1]蒋立勤,陈伟.蚓激酶或阿司匹林预防脑梗死复发的疗效分析[J].中国临床药学杂志,2006(02):106-107.DOI:10.19577/j.cnki.issn10074406.2006.02.014.
2006-03-25
2006-03-25