| 84 | 1 | 30 |
| 下载次数 | 被引频次 | 阅读次数 |
<正> 地高辛是临床上应用极其广泛的强心药。由于心力衰竭和心律失常病人需用地高辛长期治疗,根据病情有时还与其他药伍用,因此很有可能发生相互作用。不良的相互作用会导致血清地高辛浓度(Sernm DigoxinConcentration,SDC)升高,以致中毒。了解它们之间相互作用,对临床合理用药,避免不良反应具有很重要的意义。
Abstract：1 Brown DD, et al. Decreased bioavailability of digoxin due to antatids and kaolin-pection. New England Journal of Medicine 1976; 295: 1034～1037
2 Albert Ks, et al. Influence of Kaolinpectin suspension on digoxin bioaavailability. Journal of Pharmaceutical Sciences 1978; 67: 1582～1586
3 Kilgore TL, et al. Treatment of digoxin intoxication with colestipol. South Medical Journal 1982; 75: 1259
4 Floyd RA. Digoxin interaction with braw and high fiber foods. American Journal of Hospital Pharmacy 1978;35: 660
5 王宏图,等.地高辛与活性炭联合应用时的药物动力学研究.中国医院药学杂志 1986;(6) 8:1～3
6 Lindenbaum J. et al. Inhibition of digoxin by the gut flore: reversal by antibiotic therapy. New England Journalof Medicine 1981; 305: 789～794
7 Bussey HI. The influence of quinnidine and other agents on digitalis glycosides. American Heart Journal 1982;104: 289～302
8 Leahey Jr EG,et al. Quinidine-digoxin interaction: time ??course and pharmacokinetics. American Journal of Cardiology 1981; 48: 1141～1146
9 李雪宁,等.洋地黄与心律平相互作用的研究.中国临床药理学杂志 1990;6(3) :183～185
10 Moysey Jo. et al. Amiodarone increases plasma digoxin concentrations. British Medical Journal 1981; 282～272
11 Pedersen KE, et al. Digoxin-verapamil interactions. Clinical Pharmacology and Therapeutics 1981; 30: 311～316
12 郭绪昆,等.异博定对地高辛血浓度的影响及两药合用治疗房颤的临床评价.中华心血管病杂志 1991;19(6) :378
13 张家利,等.硫氮卓酮与地高辛联合服用对血清地高辛浓度的影响.中华内科杂志 1990;29(11) :646～648
14 Koren G. Interaction between digoxin and commonly coadministered drugs on children. Pediatrica 1985; 75: 1032～1037
15 Rodin S, et al. Comparative effects of verapmil and isradipine upon steady-state kinetica, Clinical Pharmacology and Therapeutics, 1988
16 Fenater PE, Hager WD, Goodman MM. Digoxin-Quinidine-spironolactone interaction. Clinical Pharmarcology and Therapentics 1984; 36: 70～73
17 Cleland J, et al. The effects of captopril onserum digoxin and urinary urea and digoxin clearances in patients with congestive heart failure. American Heart Journal 1986; 112: 130～135
18 殷民德,等.地高辛和卡托普利相互作用的监测.中国医院药学杂志 1993;13(2) :65～66
基本信息:
DOI：10.19577/j.cnki.issn10074406.1994.04.006
中图分类号:R96
引用信息:
[1]印绮平,王宏图,张静华.地高辛与其它药物的相互作用[J].临床药学,1994(04):19-22.DOI:10.19577/j.cnki.issn10074406.1994.04.006.
1994-12-30
1994-12-30