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目前1型糖尿病的治疗主要依赖胰岛素,但胰岛素只能缓解患者症状,而不能从根本上治疗1型糖尿病。2022年11月,美国食品药品监督管理局批准人源化抗分化簇3单克隆抗体teplizumab上市,用于延缓患有2期1型糖尿病的8岁及以上儿童和3期的1型糖尿病的成人的患者发病。多项临床研究已验证了teplizumab用于治疗1型糖尿病的有效性和安全性。通过对teplizumab的作用机制、临床结局和经济性进行综述,为teplizuma在我国上市后的临床应用提供参考。
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基本信息:
DOI:10.19577/j.1007-4406.2023.12.012
中图分类号:R977.15
引用信息:
[1]李杰,崔艳,钱科威,等.1型糖尿病治疗新药teplizumab的临床研究进展[J].中国临床药学杂志,2023,32(12):938-943.DOI:10.19577/j.1007-4406.2023.12.012.
基金信息:
江苏省药学会-天晴医院药学科研项目(编号Q202056)
2023-12-25
2023-12-25