中国临床药学杂志

目的 构建门诊化疗静脉用药集中调配安全模式及评价其实施效果，为肿瘤患者提供高标准的静脉用药调配服务，保障患者用药安全，提升患者就诊体验。方法 结合门诊化疗工作现状，通过信息系统支持设计、人员统筹安排和工作流程设计等举措，构建合理、完善的门诊化疗静脉用药集中调配安全模式。从不合理医嘱率、患者满意度和护士满意度3个方面对门诊化疗集中调配安全模式实施效果进行评价。结果 门诊化疗静脉用药集中调配安全模式涵盖了门诊化疗建设、运营、质控和管理多个环节，可满足门诊化疗治疗需求。该模式运行后，门诊化疗不合理医嘱比例明显降低（P <0.05）。患者在就诊流程、健康教育、护理服务方面的满意度得到了提升（P <0.05）。护士在职业防护和工作流程方面满意度也得到了提升（P <0.05）。结论 门诊化疗静脉用药集中调配安全模式将门诊化疗患者的用药全过程纳入药事质控管理体系，可全面提高患者静脉用药质量和医院服务效率，为同行开展门诊化疗工作提供参考。

AIM To incorporate outpatient chemotherapy into the pharmaceutical quality control management system, provide high-standard pharmacy intravenous admixture service for cancer patients, and ensure drug safety in patients, enhance the patient treatment experience. METHODS Based on the current situation, a reasonable and complete pharmacy intravenous admixture service for outpatient chemotherapy was established through information system support,overall personnel arrangement, workflow design, and other measures. The effect of outpatient chemotherapy was evaluated in three aspects: irrational medical orders, patient satisfaction, and nurse satisfaction. RESULTS The system covered the construction, operation, quality control, and management and met the needs of outpatient chemotherapy treatment.After the operation of the management system, the proportion of irrational medical orders decreased significantly(P <0.05). Patient satisfaction in the treatment process, health education, and nursing services increased(P < 0.05). Lastly,the fulfillment of nurses in occupational protection and the working process increased, with a statistically significant difference(P < 0.05). CONCLUSION The centralized preparation safety model for outpatient chemotherapy intravenous medication, by integrating the entire medication process for outpatient chemotherapy patients into the pharmaceutical quality control management system, can comprehensively improve the quality of intravenous drug use and hospital service efficiency, providing a reference for professionals in this field.