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目的探讨临床药师在难治耐药性铜绿假单胞菌肺炎伴菌血症患者抗感染治疗中的作用。方法临床药师参与1例心脏外科手术后合并难治耐药性铜绿假单胞菌肺炎伴菌血症患者的治疗过程,并从药动学/药效学、不良反应等方面对治疗方案进行评估,协助临床选择抗感染治疗方案。结果患者先后使用万古霉素+美罗培南、美罗培南+左氧氟沙星等方案治疗,但抗感染效果不佳,感染症状未得到明显缓解。临床药师参与治疗团队后,根据药敏试验结果与现有指南共识,将抗感染治疗方案改为左氧氟沙星+多黏菌素B后患者感染得到治愈。结论临床药师参与并协助难治耐药性铜绿假单胞菌肺炎伴菌血症患者抗感染治疗,有利于促进合理用药,提高用药有效性。
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基本信息:
DOI:10.19577/j.1007-4406.2021.03.016
中图分类号:R654.2;R563.1
引用信息:
[1]王子暄,郁骐襄,徐熠.1例心脏外科手术后合并难治耐药性铜绿假单胞菌肺炎伴菌血症患者的用药分析[J].中国临床药学杂志,2021,30(03):226-228.DOI:10.19577/j.1007-4406.2021.03.016.
2021-05-25
2021-05-25