中国临床药学杂志

目的 构建疼痛患者综合管理体系，并对其实施效果进行评价。方法 通过组建疼痛患者综合管理团队、采取医师-药师联合诊疗模式、建立疼痛患者综合管理档案以及提供以人文关怀为基石的患者教育，构建一套疼痛患者综合管理体系，为患者提供个体化用药服务。选取2023年3月至2024年2月期间就诊于疼痛门诊，实施医师-药师联合诊疗模式并建立完整档案的患者55例。利用数字分级评分法（NRS）评估患者疼痛强度变化，分析药物相关问题（DRPs）及开展镇痛药物氨酚羟考酮片的专项点评来评价疼痛患者综合管理体系的实施效果。结果 患者疼痛强度评分由干预前的（4.69±0.81）分下降到干预后的（3.24±0.69）分，差异具有高度统计学意义（P<0.01）。DRPs共发生49例次，其中用药依从性问题共33例次（占67.35%），药物安全性问题共11例次（占22.45%）,DRPs解决率达91.84%。结论 医师-药师联合诊疗模式下的疼痛患者综合管理体系，有助于改善患者依从性，提高药物治疗有效性和安全性，进一步促进合理用药。

AIM To develop a comprehensive management system for pain patients and evaluate its implementation effectiveness. METHODS The comprehensive management system for pain patients was established through multidisciplinary team formation, adoption of collaborative care model, creation of individualized management records, and humanistic patient education to deliver personalized medication services. A total of 55 patients who received physicianpharmacist collaborative care and had complete medical records in the pain clinic from March 2023 to February 2024 were enrolled. The implementation effect of the comprehensive management system for pain patients was evaluated by assessing pain intensity using the numerical rating scale(NRS), analyzing drug-related problems(DRPs), and conducting specialized reviews of oxycodone-acetaminophen tablet use. RESULTS The mean pain score decreased significantly from(4.69 ± 0.81) to(3.24 ± 0.69), indicating a statistically significant difference(P < 0.01). A total of 49 DRPs were identified, including 33(67.35%) adherence issues and 11(22.45%) safety concerns, with a resolution rate of 91.84%. CONCLUSION The comprehensive management system under the physician-pharmacist collaborative model improves patient adherence, enhances medication efficacy and safety, and promotes rational drug use.