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报道1例心脏移植术后感染解甘露醇罗尔斯顿菌病例的抗感染治疗过程。患者术后予呼吸机辅助通气，初始经验性抗感染治疗方案为利奈唑胺、伏立康唑、更昔洛韦联合头孢哌酮钠舒巴坦钠。后因肾功能不全，将抗感染治疗药物调整为美罗培南，但患者仍出现呼吸系统感染症状，痰培养及肺泡灌洗液病原学宏基因组测序（mNGS）均提示解甘露醇罗尔斯顿菌感染。临床药师根据药敏结果为患者制订个体化治疗方案，停用美罗培南，重新启用敏感的头孢哌酮钠舒巴坦钠作为核心抗感染治疗药物，并协同调整免疫抑制方案，最终患者感染得到控制，病情稳定出院。
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基本信息:
DOI：10.19577/j.1007-4406.2025.12.013
中图分类号:R969.3
引用信息:
[1]张丽燕,廖亚龙,姚亚男,等.1例心脏移植患者术后感染解甘露醇罗尔斯顿菌的抗感染治疗实践[J].中国临床药学杂志,2025,34(12):950-952.DOI:10.19577/j.1007-4406.2025.12.013.