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胰高血糖素样肽-1受体激动剂(GLP-1RAs)是一种新型抗2型糖尿病药物,具有降血糖、减重、降低血脂及降低心血管疾病发生风险等作用。然而,GLP-1RAs的疗效和不良反应存在个体差异,遗传因素可能是导致个体差异的重要原因。通过综述GLP-1RAs的药物基因组学研究进展,为GLP-1RAs的临床合理应用提供参考。
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基本信息:
DOI:10.19577/j.1007-4406.2024.11.016
中图分类号:R977.15
引用信息:
[1]刘海洋,余秋霞,钟妤,等.GLP-1受体激动剂的药物基因组学研究进展[J].中国临床药学杂志,2024,33(11):873-880.DOI:10.19577/j.1007-4406.2024.11.016.
基金信息:
国家自然科学基金面上项目(编号82374133,82074109)
2024-11-25
2024-11-25