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报道1例复方磺胺甲噁唑（SMZ/TMP）致患者血肌酐升高及胃肠道反应的病例。患者，男性，64岁，因“畏寒、发热伴咳嗽4 d”收入院，既往确诊右肺鳞癌，入院后行支气管肺泡灌洗液二代基因测序技术检查，结果提示耶氏肺孢子菌，给予SMZ/TMP抗感染治疗。治疗后患者出现血肌酐升高，并伴有恶心、呕吐。临床药师会诊，考虑很可能为SMZ/TMP引起的不良反应，根据患者肌酐清除率和耐受性，调整SMZ/TMP给药方案。经治疗，患者肺部病灶吸收，病情好转出院。
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基本信息:
DOI：10.19577/j.1007-4406.2025.09.014
中图分类号:R969
引用信息:
[1]黄雅芳,余爱荣,郝菲.1例复方磺胺甲噁唑致血肌酐升高及胃肠道反应的药学监护[J].中国临床药学杂志,2025,34(09):711-713.DOI:10.19577/j.1007-4406.2025.09.014.
2025-09-25
2025-09-25