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目的 了解我院门诊老年患者的潜在不适当用药(PIM)情况，促进合理用药。方法 随机抽取医院2024年6月38 006例老年患者(年龄≥65岁)的门诊处方单。依据2023版Beers标准，将患者分为PIM组和非PIM组，依次根据患者的年龄、性别、疾病数量和药物数量进行χ2分析，再依据结果采用二元Logistic回归模型分析发生PIM的影响因素。结果 依据2023版Beers标准，我院门诊老年患者的PIM检出率为20.29%,PIM的发生与患者的年龄、疾病数量、药物数量均相关。结论 医师和药师应提高对高频PIM药物的认知与了解，建立协作机制，强化医药沟通，以减少不必要的PIM药物数量，达到治疗过程中风险与收益之间的平衡，减少不良反应的发生。
Abstract：AIM To investigate the potentially inappropriate medication(PIM) use in elderly outpatients in our hospital and promote rational drug use. METHODS Outpatient prescriptions of elderly patients aged over 65 years in the hospital were collected. A total of 38 006 patients were classified into PIM group and non-PIM group according to the 2023 Beers criteria. Chi-square analysis was conducted on the age, gender, number of diseases, and number of medications of patients, and the influencing factors of PIM were analyzed using a binary logistic regression based on the results. RESULTS According to the 2023 Beers criteria, the detection rate of PIM among elderly outpatients in our hospital was 20.29%. The occurrence of PIM was associated with patient age, number of comorbidities, and number of medications prescribed. CONCLUSION Physicians and pharmacists should enhance their knowledge and understanding of commonly prescribed PIMs, establish collaborative mechanisms to strengthen interdisciplinary communication, and minimize unnecessary PIM prescribing. These measures will optimize the risk-benefit balance in treatment and reduce adverse drug reactions.
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基本信息:
DOI：10.19577/j.1007-4406.2025.08.003
中图分类号:R95
引用信息:
[1]祝新峰,迟丹怡.基于2023版Beers标准评估我院门诊老年患者的用药情况[J].中国临床药学杂志,2025,34(08):576-582.DOI:10.19577/j.1007-4406.2025.08.003.
2025-08-25
2025-08-25