姜秋红;程能能;高惠君;

• 1:复旦大学药学院药理学教研室
• 2:复旦大学附属妇产科医院药剂科
• 3:上海市食品药品安全研究中心

摘要(Abstract)：

蛋白酪氨酸激酶(PTK)是一类具有酪氨酸激酶活性的蛋白质,在细胞内的信号转导通路中占据了十分重要的地位。其中,P【-3K/AKT/mTOR信号通路和Ras/MARK信号通路与肿瘤的发生、发展、侵润及转移密切相关,已成为当前抗肿瘤药物研究的重要靶点。本文就近年来以这2条信号转导通路为靶点的抗肿瘤药物作一综述。

关键词(KeyWords)： 肿瘤;信号通路;mTOR抑制剂;法尼基转移酶抑制剂

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 姜秋红;程能能;高惠君;

Email:

DOI: 10.19577/j.cnki.issn10074406.2011.06.019

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