胺碘酮注射液致急性肝衰竭1例A case report of acute liver failure induced by amiodarone injection
杨欣;袁世加;周杭;方庆;周磊;喻倩;邓连力;冉莎莎;
摘要(Abstract):
报道1例胺碘酮注射液致急性肝衰竭的病例。患者为老年男性,因急性心肌梗死(非ST段抬高型)入院治疗。住院期间因频发室上性心动过速而加胺碘酮注射液治疗(首剂150 mg,缓慢iv;之后在15 h内持续静脉泵入750 mg),1 d后出现肝功能衰竭(ALT1 509 U·L(-1),AST 2 556 U·L(-1),AST 2 556 U·L(-1))。经停用胺碘酮注射液并予保肝治疗,5 d后肝功能逐渐恢复。采用RUCAM因果关系评估量表,得分为7分,急性肝功能衰竭与胺碘酮注射液之间相关性为极可能。
关键词(KeyWords): 胺碘酮;急性肝衰竭;RUCAM因果关系评估量表;肝细胞损伤型;保肝药
基金项目(Foundation):
作者(Authors): 杨欣;袁世加;周杭;方庆;周磊;喻倩;邓连力;冉莎莎;
DOI: 10.19577/j.1007-4406.2022.01.014
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