两性霉素B与两性霉素B脂质体不良反应文献分析
刘晓东,李佳楠,孙浩,肇丽梅,菅凌燕
摘要(Abstract)：
目的探讨两性霉素B与两性霉素B脂质体所致不良反应的一般规律和特点,为临床合理用药提供参考。方法在CHKD期刊全文数据库、维普医药信息系统、万方数据医药系统、Medline数据库检索1977-2013年有关两性霉素B与两性霉素B脂质体不良反应的文献,并进行统计分析。结果共收集两性霉素B不良反应病例40例,两性霉素B脂质体不良反应病例24例,涉及的反应系统有泌尿系统、肝胆系统、离子紊乱、循环系统和消化系统等。结论两性霉素B与两性霉素B脂质体引起的不良反应相似,但应注意某些特殊不良反应。临床上应该做到合理用药,减少不良反应的发生。
关键词(KeyWords)： 两性霉素B;两性霉素B脂质体;药品不良反应;文献分析
基金项目(Foundation): 辽宁省教育厅课题资助(编号L2010578)
作者(Author): 刘晓东,李佳楠,孙浩,肇丽梅,菅凌燕
DOI: 10.19577/j.cnki.issn10074406.2014.04.015
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