临床药师对1例胎盘部位滋养细胞肿瘤化疗并发带状疱疹患者的药学监护Pharmaceutical care for a patient with herpes zoster complicated by chemotherapy of placental trophoblastic tumor by clinical pharmacists
黄亭;王先利;
摘要(Abstract):
目的探讨临床药师在胎盘部位滋养细胞肿瘤化疗并发带状疱疹患者治疗中的作用。方法临床药师参与1例胎盘部位滋养细胞肿瘤患者多药化疗后发生带状疱疹的治疗。通过查阅文献,分析不良反应发生的可能原因;同时参与治疗方案的调整,并为患者提供全程药学监护。结果患者经治疗后,带状疱疹症状得到明显好转,顺利完成后续化疗,未见明显不良反应发生。结论临床药师应积极参与罕见病的治疗过程,协助医师处理不良反应,保障患者用药安全。
关键词(KeyWords): 临床药师;胎盘部位滋养细胞肿瘤;带状疱疹;不良反应;药学监护
基金项目(Foundation): 上海市“医苑新星”青年医学人才培养计划[编号:沪卫计人事(2019)72号]
作者(Author): 黄亭;王先利;
Email:
DOI: 10.19577/j.1007-4406.2021.01.013
参考文献(References):
- [1]赵峻,向阳.胎盘部位滋养细胞肿瘤的诊治[J].中国实用妇科与产科杂志,2017,33(4):353.
- [2]ZHAO J,LV W G,FENG F Z,et al.Placental site trophoblastic tumor:a review of 108 cases and their implications for prognosis and treatment[J].Gynecol Oncol,2016,142(1):102.
- [3]SCHMID P,NAGAI Y,AGARWAL R,et al.Prognostic markers and long-term outcome of placental-site trophoblastic tumours:a retrospective observational study[J].Lancet,2009,374(9683):48.
- [4]NGAN H Y S,SECKL M J,BERKOWITZ R S,et al.Update on the diagnosis and management of gestational trophoblastic disease[J].Int J Gynaecol Obstet,2018,143(Suppl 2):79.
- [5]HOROWITZ N S,GOLDSTEIN D P,BERKOWITZ R S.Placental site trophoblastic tumors and epithelioid trophoblastic tumors:Biology,natural history,and treatment modalities[J].Gynecol Oncol,2017,144(1):208.
- [6]王官清,李晓霞.带状疱疹的临床流行病学及预防[J].中国皮肤性病学杂志,2018,32(11):1325.
- [7]MAO J,MCPHEETERS J T,FINELLI L.Healthcare utilization and costs among patients with Herpes zoster and solid tumor malignancy on chemotherapy:a retrospective cohort study[J].Medicine (Baltimore),2017,96(48):e8746.
- [8]王恩文,王东林,马惠文,等.57例恶性肿瘤合并带状疱疹的回顾性分析[J].重庆医学,2015,44(26):3655.
- [9]彭光玲,李惠.早期足量抗病毒治疗带状疱疹临床疗效观察[J].重庆医科大学学报,2013,38(3):311.
- [10]SCHMADER K.Herpes zoster[J].Ann Intern Med,2018,169(3):ITC17.
- [11]BRUXELLE J,PINCHINAT S.Effectiveness of antiviral treatment on acute phase of Herpes zoster and development of post herpetic neuralgia:review of international publications[J].Médecine et Maladies Infect,2012,42(2):53.
- [12]LIN W R,LIN H H,LEE S S,et al.Comparative study of the effi cacy and safety of valaciclovir versus acyclovir in the treatment of Herpes zoster[J].J Microbiol Immunol Infect,2001,34(2):138.
- [13]YALDIZ M,SOLAK B,KARA R O,et al.Comparison of famciclovir,valaciclovir,and brivudine treatments in adult immunocompetent patients with Herpes zoster[J].Am J Ther,2018,25(6):e626.
- [14]ONO F,YASUMOTO S,FURUMURA M,et al.Comparison between famciclovir and valacyclovir for acute pain in adult Japanese immunocompetent patients with Herpes zoster[J].JDermatol,2012,39(11):902.
- [15]方锐华,杨捷,莫友.大剂量口服伐昔洛韦片治疗带状疱疹的疗效观察[J].皮肤性病诊疗学杂志,2013,20(1):38.
- [16]BADEN L R,SWAMINATHAN S,ANGARONE M,et al.Prevention and treatment of cancer-related infections,version2.2016,NCCN clinical practice guidelines in oncology[J].JNatl Compr Canc Netw,2016,14(7):882.
- [17]中国医师协会皮肤科医师分会带状疱疹专家共识工作组.带状疱疹中国专家共识[J].中华皮肤科杂志,2018,51(6):403.