支气管扩张症伴施氏假单胞菌感染患者的抗感染治疗分析及不良反应监护Analysis of anti-infective treatment and monitoring of adverse reactions in patients with bronchiectasis complicated with Pseudomonas stutzeri
郑盼盼;陈锡创;洪远;陈艳华;韩美玲;王燕;
摘要(Abstract):
目的探讨支气管扩张症伴施氏假单胞菌感染的抗感染治疗的特点及开展药学监护的必要性。方法以临床药师参与1例痰培养示施氏假单胞菌阳性的支气管扩张患者的抗感染治疗经过为例,结合相关文献及患者疾病特点,阐述治疗各阶段抗感染药物的合理性和药学监护要点。结果该患者在入院后予头孢他啶抗感染治疗4 d后感染症状未得到有效控制,在临床药师推荐下改用哌拉西林钠他唑巴坦联合阿奇霉素的抗感染治疗方案后,细菌得到清除,患者痊愈出院。治疗期间,临床药师对抗感染药物的不良反应进行了监护,及时发现和解决了患者用药期间出现的腹泻、腹痛等不良反应。结论支气管扩张伴施氏假单胞菌感染治疗时需考虑耐药性,选择合适的抗感染药物足疗程治疗至关重要;在治疗过程中监护药物不良反应,在保障安全用药方面起着一定的积极作用。
关键词(KeyWords): 施氏假单胞菌;支气管扩张症;抗感染治疗;临床药师
基金项目(Foundation): 无锡市卫健委中青年拔尖人才资助计划(编号BJ2020087、HB2020115)
作者(Author): 郑盼盼;陈锡创;洪远;陈艳华;韩美玲;王燕;
Email:
DOI: 10.19577/j.1007-4406.2021.01.014
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