顺式阿曲库铵药动学和药效学研究进展
郭建荣;卢慧琴;陈小非;
摘要(Abstract):
<正>顺式阿曲库铵是构成阿曲库铵消旋混合物的10种同分异构体之一,为顺式旋光异构体。与阿曲库铵一样,它主要通过与运动终板胆碱能受体竞争性结合而发挥肌松作用。由于顺式阿曲库铵起效及恢复迅速,不释放组胺,对心血管影响小,无蓄积作用,代谢产物无毒性及肌松效应,得以在临床上广泛应用。我们就其药动学、药效学、临床应用和研究
关键词(KeyWords):
基金项目(Foundation):
作者(Authors): 郭建荣;卢慧琴;陈小非;
DOI: 10.19577/j.cnki.issn10074406.2010.03.022
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