MTT法和双琼脂MTT法测肿瘤药敏及其临床应用CLINICAL USEFULNESS OF CHEMOSENSITIVITY TESTING USING THE MTT METHOD AND DOUBLE-LAYER AGAROSE MTT METHOD
翟晓波,张毅,宗黎琼,陆瑶华,沈炜明,李炳生
摘要(Abstract):
本实验用MTT法测定了258例恶性肿瘤对17种常用抗癌药的体外敏感性,其中30例用MTT法和双琼脂MTT法同时测定,结果显示后者抑制率高于前者.有25例用MTT法测定的实体瘤可评价其近期疗效,其中11例药敏试验显示不敏感而临床化疗无效,另14例抗癌药体外敏感而临床化疗8例有效,抗癌药体外敏感性和临床疗效总符合率为80%.
关键词(KeyWords): MTT法;琼脂;化疗敏感性
基金项目(Foundation):
作者(Author): 翟晓波,张毅,宗黎琼,陆瑶华,沈炜明,李炳生
DOI: 10.19577/j.cnki.issn10074406.1996.03.004
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